Coronavirus - Part Two.

[Longcol 602]

55 minutes ago, apelike said:

Just had a quick google and cant see any results on vaccine software modelling so I presume that it can't be done. As onewheeldave said there has been no long term safety testing so far... because this has all been developed and the vaccination programme done relatively quickly so only time can be the judge on that one. It's the reason why no effects to the vaccines were initially known about and have only recently been discovered given the time frames involved.

It seems to be having a very good effect on reducing hospitalisations and deaths.

[Bargepole23 337]

2 hours ago, apelike said:

Just had a quick google and cant see any results on vaccine software modelling so I presume that it can't be done. As onewheeldave said there has been no long term safety testing so far... because this has all been developed and the vaccination programme done relatively quickly so only time can be the judge on that one. It's the reason why no effects to the vaccines were initially known about and have only recently been discovered given the time frames involved.

https://academic.oup.com/nar/article/49/W1/W671/6261783

 

Amongst others. Seems like computational tools play an important role in vaccine design. I don't claim to understand the science but on first inspection it seems like tools are available to select and predict candidates on efficacy and other metrics.

 

Other papers draw a distinction between traditional vaccine development methods, and modern computational methods.

[rogets 141]

We got an underground shelter at the bottom of the garden, and we have vegetables growing 

 

We got a container to catch rainwater as well as water purification tablets, we bought 100s of purification tablets

 

We have stocked up on beans and bought 3 huskys to pull a sledge on wheels as our method of transport. 

 

Once the petrol runs out, cars no longer work.

 

We are getting ready for the worst 

 

We are also stocking up on batteries, candles, torches etc... I think we are very much prepared 

[Carbuncle 0]

 

30 minutes ago, Bargepole23 said:

https://academic.oup.com/nar/article/49/W1/W671/6261783

 

Amongst others. Seems like computational tools play an important role in vaccine design. I don't claim to understand the science but on first inspection it seems like tools are available to select and predict candidates on efficacy and other metrics.

 

Other papers draw a distinction between traditional vaccine development methods, and modern computational methods.

The computational tools you have drawn attention to seem to be about one particular part of the process: the selection of an epitope, that is the piece of the pathogen which is going to end up being recognised by the adaptive immune system. This is more to do with efficacy, a better selection of epitope means a more 'reliable' adaptive immune response. I am dubious that any satisfactory modelling exists for side effects. I am not saying this because I have any expertise, it's just that biology is soooo complicated relative to the human understanding of biology. The 'model' that does seem to exist, call it 'the judgement of the experts' is that because the body will tidy away the components of the vaccine fairly quickly and because the adaptive immune response triggered by the vaccine should fairly fully emerge within a couple of weeks then any side effects will start fairly soon after vaccination.

 

The clinical trials that were conducted did detect side effects and a whole lot of instances of them. The common side effects were all judged tolerable and seemed to be the kind of thing you would expect from a vaccine. In terms of severe 'reactions' in the clinical trials, these were  very rare and appeared at similar frequencies amongst the vaccinated and the controls. In fact by some odd chance, I think for each of  the three vaccines where I had a look at the data (AstraZeneca, Pfizer and Moderna) there were more of these severe 'reactions' amongst the control group than the vaccinated group.

 

The clinical trials could not be expected to detect certain kinds of side effects. If you do a trial with a few tens of thousands of people you should not expect to pick up a side effect that affects 1 in 100,000 vaccine recipients. This is why it is reasonable that the blood clots were not picked up by the AstraZeneca clinical trials. The blood clots, by the way, are thus far thought to have killed 71 people in the UK according to the latest information I have seen. Likewise if you give an emergency use authorization to a vaccine after you have only collected a few months of the trial data then you did not of course  give the trial the opportunity to pick up long term side effects and are instead relying on expert judgement.

 

 

 

2 hours ago, Longcol said:

It seems to be having a very good effect on reducing hospitalisations and deaths.

I agree.

[Baron99 795]

27 minutes ago, rogets said:

We got an underground shelter at the bottom of the garden, and we have vegetables growing 

 

We got a container to catch rainwater as well as water purification tablets, we bought 100s of purification tablets

 

We have stocked up on beans and bought 3 huskys to pull a sledge on wheels as our method of transport. 

 

Once the petrol runs out, cars no longer work.

 

We are getting ready for the worst 

 

We are also stocking up on batteries, candles, torches etc... I think we are very much prepared 

No toilet rolls.   Oh, school boy error.  Unless you're going to use cabbage leaves? 

Edited July 15, 2021 by Baron99

[Guest sibon]

3 minutes ago, Baron99 said:

No toilet rolls.   Oh, school boy error.  Unless you're going to use cabbage leaves? 

You don’t need toilet rolls if you are full of ****.

 

It is only when you release it that the paper is required.

[butlers 261]

Think a couple of weeks back sheffield hospitals had 3 covid in patients 

Up to 40 now ,increased 48 % in the last week of reporting.

 

[The_DADDY 3,475]

Oh my god just list to this maniac 

She should be struck off, deplatformed, arrested and charged... 

 

 

[Longcol 602]

7 minutes ago, The_DADDY said:

Oh my god just list to this maniac 

She should be struck off, deplatformed, arrested and charged... 

 

 

Her medical specialisms seem to be Obs & Gynae - doesn't appear to have any professional experience of vaccination.

 

https://uk.linkedin.com/in/tess-lawrie-71b53652

[butlers 261]

She has also backed ,Ivermectin.

 

I think today the lead study of it has been  completely repudiated

In fact there's 3 questionable things in 2 sentences that she said.

 

 

[Carbuncle 0]

18 minutes ago, The_DADDY said:

Oh my god just list to this maniac 

She should be struck off, deplatformed, arrested and charged... 

So you are posting somebody who you do not believe, somebody whose arguments you do not agree with. Do I have that right? But you decline to post a link to data and argument that you do believe in.

[butlers 261]

I was being generous,but a bit if furthur reading of her paper from June 16 and the fact she's tied up with the ," America's Frontline doctors" should set arm bells clanging

America's Frontline Doctors of course is the group who had " demon sperm " as one of thier leading lights  at the white house  briefing 

She claimed to have cured 1000  covid patients and coincidentally sold  dubious health supplicants