petemcewan
-
Content Count
1,933 -
Joined
-
Last visited
Posts posted by petemcewan
-
-
Riffraff.
I'm registered with Heeley Green Surgery. You are quite right the Belgrave Med Centre. Might I suggest you phone Heeley Surgery and ask them about when she might receive her vaccination.
When I phoned-about 10 days ago-they informed me that they were working through the upper age group and would get round the 70+
about the 11th Jan. So it's worth a inquiry.
-
Cyclecar.
Congrats. Had my BNT162b2 vaccination on Thursday 14th Jan,16. 20hrs , at the Matthews Medical Centre.
It all went very smoothly and professionally. It was a bit of an epic getting there. Had to put chains on the front -winter tyres- wheels of my little Suzuki Ignis 4x4 to get out of my Crescent. My God! Winter tryes,chains and 4x4 ,and this is in Sheffield -and not the Alps.
I'm very pleased with the Vax I was given. It has a very good CD4/CD8 cell profile.
As a consequence of having the Vax.I'm less anxious now.
Note: No side effects whatsoever.
PS, No date given on my card for my second one.
-
Apelike,
Thanks for that very interesting link.
If you go to the Comments Section .Janet provides an equally interesting link.
-
Pfizer vaccine appears to work against variant and S.A variant. Caution , The report is a pre-print and has not yet been peer reviewed. But if true,then this is very good news indeed.
https://www.sciencemediacentre.org/expert-reaction-to-the-new-variant-of-sars-cov-2/
Masses of opinions in the above link. Well worth a browse through if you want to jog along with the Profs and Experts.
-
Fancypants.
That is sad news. I do hope your neighbour recovers.
Hospitals are doing their best to mitigate hospital transmission of Cov-19.
The link I provide will give you an insight as to what is going on.
I must admit,that the last thing I want is to be admitted into hospital for anything other than Cov019 treatment.
https://fullfact.org/health/coronavirus-transmission-hospitals/
-
For those of you who are interested in this debate. My own personal opinion of this brand of ethics, is that it's a prime example of repugnant authoritarian Utilitarianism. An example of how to tailor a proposition to the outcome that is desired.
I sincerely hope the UK does not adopted the strategy outlined
https://jme.bmj.com/content/early/2020/11/09/medethics-2020-106821
-
According to Heeley Green Surgery I'm due mine probably next week. It will be administered at Belgrave Medical Centre. As a boomer, I don't rely care which one I get-the sooner the better. But, and I don't want to offend anybody,perish the thought;what really gets on my pip is all the virtue signalling ,surround those boomers who want to exercise some choice.
The following is worth knowing.
https://www.prevention.com/health/a35118263/astrazeneca-vs-pfizer-vs-moderna-covid-19-vaccine/
Stay safe .
-
QuoteRubbish. Where are you getting these fairytales ? My parents went for their second jab today and were told that everyone had turned up for their appointment.
Taken from the comments section after the article.
-
Organgrinder,
I don't necessarily disagree with you. I put the Thread on to stimulate some discussion.
The quotes are from Nature,and the BMJ. .Both journals carry some weight in the field of medicine.
From my reading the "asymptomatic superspreader " seems to be more pseudo
science than a finding from well conducted epidemiology.
The following is what I've been able to glean from all the reading I've been doing since May 2020.
Infectiousness is highest within 5 day period immediately before and shortly after symptoms appear.
Anyway,not every transmission is synonymous with "superspread" and that term should be used cautiously.
It appears to me that in the field of science reporting during this pandemic, there's a syndrome of “some data beats no data”.
During the early days of the pandemic there has been a plethora of corona virus clinical reports /pre-print scientific papers. And those papers have been superseded by larger, more well-controlled ones . Some of those early observations have held up, and some of them haven’t.
So we need to vigilant in respect of the quality of the science that is being pushed our way.
I agree with you entirely that we should follow the advice. But we should examine that advice to the best of our abilities. In the end-like you say,"opposing views".We have to make a choice on who to believe.
IMO there is every reason to think that the amount and length of time of virus shedding by asymptomatics will be reduced-if not-eliminated- through vaccination.
However,as I see it,most transmission is in the home, where staying home doesn't stop symptomatic transmission. So on it will go on-for awhile.
As far as having a sterilising vaccine. Well,the Oxford people claim that their vax will reduce asymptomatic virus shedding. So get that vax into bodies-and quick.
I'll finish by putting my mouth where the money is. The existence of the Asmptomatic Superpreader is a myth.
-
Enntee,
Quote taken from the link I provided.This contradicts a lot of received wisdom that supports asymptomatics being a significant vector in the spreading of Covid-19.
Note: BMJ ,12-20%
QuoteThe citywide nucleic acid screening of SARS-CoV-2 infection in Wuhan recruited nearly 10 million people, and found no newly confirmed cases with COVID-19. The detection rate of asymptomatic positive cases was very low, and there was no evidence of transmission from asymptomatic positive persons to traced close contacts. There were no asymptomatic positive cases in 96.4% of the residential communities.
EditorialsAsymptomatic transmission of covid-19
BMJ 2020; 371 doi: https://doi.org/10.1136/bmj.m4851 (Published 21 December 2020)Cite this as: BMJ 2020;371:m4851- Correspondence to: A M Pollock Allyson.Pollock@newcastle.ac.uk
What we know, and what we don’t
The UK’s £100bn “Operation Moonshot” to roll out mass testing for covid-19 to cities and universities around the country raises two key questions. How infectious are people who test positive but have no symptoms? And, what is their contribution to transmission of live virus?
Unusually in disease management, a positive test result is the sole criterion for a covid-19 case. Normally, a test is a support for clinical diagnosis, not a substitute. This lack of clinical oversight means we know very little about the proportions of people with positive results who are truly asymptomatic throughout the course of their infection and the proportions who are paucisymptomatic (subclinical), presymptomatic (go on to develop symptoms later), or post-infection (with viral RNA fragments still detectable from an earlier infection).
Earlier estimates that 80% of infections are asymptomatic were too high and have since been revised down to between 17% and 20% of people with infections.12 Studies estimating this proportion are limited by heterogeneity in case definitions, incomplete symptom assessment, and inadequate retrospective and prospective follow-up of symptoms, however.3 Around 49% of people initially defined as asymptomatic go on to develop symptoms.45
It’s also unclear to what extent people with no symptoms transmit SARS-CoV-2. The only test for live virus is viral culture. PCR and lateral flow tests do not distinguish live virus. No test of infection or infectiousness is currently available for routine use.678 As things stand, a person who tests positive with any kind of test may or may not have an active infection with live virus, and may or may not be infectious.9
The relations between viral load, viral shedding, infection, infectiousness, and duration of infectiousness are not well understood. In a recent systematic review, no study was able to culture live virus from symptomatic participants after the ninth day of illness, despite persistently high viral loads in quantitative PCR diagnostic tests. However, cycle threshold (Ct) values from PCR tests are not direct measures of viral load and are subject to error.10
While viral load seems to be similar in people with and without symptoms, the presence of RNA does not necessarily represent transmissible live virus. The duration of viral RNA shedding (interval between first and last positive PCR result for any sample) is shorter in people who remain asymptomatic, so they are probably less infectious than people who develop symptoms.11
-
Is there something not quite right in the science ?
https://www.nature.com/articles/s41467-020-19802-w
-
Taking two different vaccines might become a very relevant topic if travel restrictions will mandate certain vaccines ,as prerequisites for entering different countries .
At the moment you don't get a choice of what vaccine you'll get. The Gov has got control of it.
Imagine if the Biden administration require a vaccination with an FDA approval before being allowed to enter the US.
Then the Chines government requires FDA approved vaccine for entering China.
And so on.
-
Numerous times this morning I heard various news channels refer to the "new Co-19 variant" as being a "new strain".
It is not a new stain.
https://www.independent.co.uk/news/health/covid-strain-mutation-variant-england-b1777724.html
Link explains:Strain, Variant, mutation.
-
My apologies to the Forum. I'm erasing the RT reference. I got it utterly wrong.
If fact, Cross Talk was attacking :The Great Reset Project,Technocracy and Junk rt PCR Tests.
I'll leave the link in place. Some may find it interesting.
-
.
https://www.rt.com/op-ed/507336-great-reset-world-economic-forum/
In addition, I will be "well glad"(young person's parlance) to see the back of 2020.
In anticipation,I wish everybody on the Forum,a healthy 2021.
Note: I wish the Gov would hurry up with the Vaccination Programme.
The Russians are already vaccinating 60yr old and upwards.
-
El Cid.
I cannot answer you first question.
But without boring you with the whole of the first link I provided.
The following is taken from the Discussion section.
QuoteThe objective of this study was to evaluate the proof-of-concept of a new SARS-CoV vaccine strategy based on a standard measles vaccine engineered to express the SARS-CoV spike protein. This strategy might provide a safe recombinant vaccine to protect from SARS-CoV in the regions that might become affected by SARS-CoV re-emergence.
I put the thread on because it demonstrates to me how some people don't wait around. They get up and get the get go-and take charge of their future.
We can't get a straight answer as to how many people have already been vaccinated. So my mate thought ,"bug... " that. If it's good for a mouse. It might give me some protection".
The mRNA vaccine s will more than likely outstrip this MMR vax.
But,Hey Ho,Jingle Bells. When needs must.
-
A close friend of mine, who is 65, has payed for a MMR vaccination(£45).
The vaccination was administered at Superdrug in London.
He explained to me that there was some evidence that the MMR vax gave some protection against Cov-19.
https://www.sciencedirect.com/science/article/pii/S0042682214000051
Furthermore ,he explained that he wasn't going to wait around until
his GP called him for vaccination,"To damn slow.Better some protection now. It's worth a punt".
If Superdrug can dish out all kinds of vaccines. Will they be dishing out Covid -19 vax ?
-
This is worth getting your head around-just to keep one sane.
Now that we have another variant-there will possible be more.
This is what we find. BioNTec says they can make a vaccine against Cov variant in six weeks. Now that is good news.
-
A thing to watch out for is the theory that the varient(s) are a consequence of treatments and vaccine.
To early to tell ,re ,vaccines.
Varients brewing up in immune compromised people!
It's all theory.There's no scientific proof of any of it.
The "News" keeps rolling out all these Profs ,Dr's ,Epidemiologists and god knows who. All spouting "authoritatively" their own pet theories.
Who are they? Where have they come from? Who cares?
IT's DOING ME HEAD IN !
-
Abbyedges
Couldn't agree with you more.
Maybe get the BioNTech- first dose -out to as many people as possible-then follow up later.
-
Melthebell
This is for you.
Timely,honest communication from a source an audience deems credible is essential to containing fear during a Pandemic.
It's the alarming tone used in media coverage that unnerves me.
Stay well and enjoy you Christmas and New Year.
-
Another media campaign of frightening the B Jesus out of everybody.
Variations happen all the time, this is nothing new.
New strains are tracked and vaccines can be updated - especially mRNA vaccines.
As it goes, there is no need for mass panic about this particular variation.
There is no evidence that any Cov-19 therapeutics has given rise to the mutation.Fears have been expressed about the effectiveness of the current vaccines. Peddling the notion that they won't work is scaremongering.In addition, what's not helpful, is having one of the country's most senior politicians,telling everybody we're put of control.
Get some giddy up in the vaccination programme.
-
El Cid
You may find this interesting.
https://www.sciencedirect.com/science/article/pii/S0092867420308175#bib3
Especially Para 3 in the Main Text.
QuoteStill, these data do not prove that G614 is more infectious or transmissible than viruses containing D614. And because of that, many questions remain on the potential impacts, if any, that D614G has on the COVID-19 pandemic
I'm holding onto this:
QuoteThe same team found clinical evidence to suggest that people with this variant had more virus particles in their upper respiratory tracts than people with other variants. That said, despite this extra “viral load,” their illness appeared to be no more severe.
Taken from the link you provided.
-
Enntee
Thank you for that direction.
QuoteThe two earliest sampled genomes that belong to the B.1.1.7 lineage were collected on 20-Sept-2020 in Kent and another on 21-Sept-2020 from Greater London.
How on earth did UCL miss that one ?
Coronavirus - Part Two.
in General Discussions
Posted
Tinfoilhat.
Yes. "Sit in that room over there. You can leave at the time written on the piece of paper I've just given you".
Unfortunately, no tea and biscuits.