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petemcewan

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Everything posted by petemcewan

  1. According to Heeley Green Surgery I'm due mine probably next week. It will be administered at Belgrave Medical Centre. As a boomer, I don't rely care which one I get-the sooner the better. But, and I don't want to offend anybody,perish the thought;what really gets on my pip is all the virtue signalling ,surround those boomers who want to exercise some choice. The following is worth knowing. https://www.prevention.com/health/a35118263/astrazeneca-vs-pfizer-vs-moderna-covid-19-vaccine/ Stay safe .
  2. Taken from the comments section after the article.
  3. Organgrinder, I don't necessarily disagree with you. I put the Thread on to stimulate some discussion. The quotes are from Nature,and the BMJ. .Both journals carry some weight in the field of medicine. From my reading the "asymptomatic superspreader " seems to be more pseudo science than a finding from well conducted epidemiology. The following is what I've been able to glean from all the reading I've been doing since May 2020. Infectiousness is highest within 5 day period immediately before and shortly after symptoms appear. Anyway,not every transmission is synonymous with "superspread" and that term should be used cautiously. It appears to me that in the field of science reporting during this pandemic, there's a syndrome of “some data beats no data”. During the early days of the pandemic there has been a plethora of corona virus clinical reports /pre-print scientific papers. And those papers have been superseded by larger, more well-controlled ones . Some of those early observations have held up, and some of them haven’t. So we need to vigilant in respect of the quality of the science that is being pushed our way. I agree with you entirely that we should follow the advice. But we should examine that advice to the best of our abilities. In the end-like you say,"opposing views".We have to make a choice on who to believe. IMO there is every reason to think that the amount and length of time of virus shedding by asymptomatics will be reduced-if not-eliminated- through vaccination. However,as I see it,most transmission is in the home, where staying home doesn't stop symptomatic transmission. So on it will go on-for awhile. As far as having a sterilising vaccine. Well,the Oxford people claim that their vax will reduce asymptomatic virus shedding. So get that vax into bodies-and quick. I'll finish by putting my mouth where the money is. The existence of the Asmptomatic Superpreader is a myth.
  4. Enntee, Quote taken from the link I provided. This contradicts a lot of received wisdom that supports asymptomatics being a significant vector in the spreading of Covid-19. Note: BMJ ,12-20% Editorials Asymptomatic transmission of covid-19 BMJ 2020; 371 doi: https://doi.org/10.1136/bmj.m4851 (Published 21 December 2020)Cite this as: BMJ 2020;371:m4851 Read our latest coverage of the coronavirus outbreak Article Related content Metrics Responses Allyson M Pollock, professor of public health1, James Lancaster, independent researcher2 Author affiliations Correspondence to: A M Pollock Allyson.Pollock@newcastle.ac.uk What we know, and what we don’t The UK’s £100bn “Operation Moonshot” to roll out mass testing for covid-19 to cities and universities around the country raises two key questions. How infectious are people who test positive but have no symptoms? And, what is their contribution to transmission of live virus? Unusually in disease management, a positive test result is the sole criterion for a covid-19 case. Normally, a test is a support for clinical diagnosis, not a substitute. This lack of clinical oversight means we know very little about the proportions of people with positive results who are truly asymptomatic throughout the course of their infection and the proportions who are paucisymptomatic (subclinical), presymptomatic (go on to develop symptoms later), or post-infection (with viral RNA fragments still detectable from an earlier infection). Earlier estimates that 80% of infections are asymptomatic were too high and have since been revised down to between 17% and 20% of people with infections.12 Studies estimating this proportion are limited by heterogeneity in case definitions, incomplete symptom assessment, and inadequate retrospective and prospective follow-up of symptoms, however.3 Around 49% of people initially defined as asymptomatic go on to develop symptoms.45 It’s also unclear to what extent people with no symptoms transmit SARS-CoV-2. The only test for live virus is viral culture. PCR and lateral flow tests do not distinguish live virus. No test of infection or infectiousness is currently available for routine use.678 As things stand, a person who tests positive with any kind of test may or may not have an active infection with live virus, and may or may not be infectious.9 The relations between viral load, viral shedding, infection, infectiousness, and duration of infectiousness are not well understood. In a recent systematic review, no study was able to culture live virus from symptomatic participants after the ninth day of illness, despite persistently high viral loads in quantitative PCR diagnostic tests. However, cycle threshold (Ct) values from PCR tests are not direct measures of viral load and are subject to error.10 While viral load seems to be similar in people with and without symptoms, the presence of RNA does not necessarily represent transmissible live virus. The duration of viral RNA shedding (interval between first and last positive PCR result for any sample) is shorter in people who remain asymptomatic, so they are probably less infectious than people who develop symptoms.11
  5. Is there something not quite right in the science ? https://www.nature.com/articles/s41467-020-19802-w
  6. Janie48 Happy New Year/ Nice version of the original Tom Waits recording. Searching for the normal in 2021.
  7. Taking two different vaccines might become a very relevant topic if travel restrictions will mandate certain vaccines ,as prerequisites for entering different countries . At the moment you don't get a choice of what vaccine you'll get. The Gov has got control of it. Imagine if the Biden administration require a vaccination with an FDA approval before being allowed to enter the US. Then the Chines government requires FDA approved vaccine for entering China. And so on.
  8. Numerous times this morning I heard various news channels refer to the "new Co-19 variant" as being a "new strain". It is not a new stain. https://www.independent.co.uk/news/health/covid-strain-mutation-variant-england-b1777724.html Link explains:Strain, Variant, mutation.
  9. My apologies to the Forum. I'm erasing the RT reference. I got it utterly wrong. If fact, Cross Talk was attacking :The Great Reset Project,Technocracy and Junk rt PCR Tests. I'll leave the link in place. Some may find it interesting.
  10. . https://www.rt.com/op-ed/507336-great-reset-world-economic-forum/ In addition, I will be "well glad"(young person's parlance) to see the back of 2020. In anticipation,I wish everybody on the Forum,a healthy 2021. Note: I wish the Gov would hurry up with the Vaccination Programme. The Russians are already vaccinating 60yr old and upwards.
  11. El Cid. I cannot answer you first question. But without boring you with the whole of the first link I provided. The following is taken from the Discussion section. I put the thread on because it demonstrates to me how some people don't wait around. They get up and get the get go-and take charge of their future. We can't get a straight answer as to how many people have already been vaccinated. So my mate thought ,"bug... " that. If it's good for a mouse. It might give me some protection". The mRNA vaccine s will more than likely outstrip this MMR vax. But,Hey Ho,Jingle Bells. When needs must.
  12. A close friend of mine, who is 65, has payed for a MMR vaccination(£45). The vaccination was administered at Superdrug in London. He explained to me that there was some evidence that the MMR vax gave some protection against Cov-19. https://www.sciencedirect.com/science/article/pii/S0042682214000051 Furthermore ,he explained that he wasn't going to wait around until his GP called him for vaccination,"To damn slow.Better some protection now. It's worth a punt". If Superdrug can dish out all kinds of vaccines. Will they be dishing out Covid -19 vax ?
  13. This is worth getting your head around-just to keep one sane. Now that we have another variant-there will possible be more. This is what we find. BioNTec says they can make a vaccine against Cov variant in six weeks. Now that is good news. https://www.sciencemediacentre.org/expert-reaction-to-the-new-variant-of-sars-cov-2/?cli_action=1608748040.476 https://www.forbes.com/sites/roberthart/2020/12/22/pfizer-biontech-moderna-test-vaccines-against-new-covid-19-variant-spreading-across-uk/?sh=f54062816a34 https://www.sciencemediacentre.org/tag/covid-19/
  14. A thing to watch out for is the theory that the varient(s) are a consequence of treatments and vaccine. To early to tell ,re ,vaccines. Varients brewing up in immune compromised people! It's all theory.There's no scientific proof of any of it. The "News" keeps rolling out all these Profs ,Dr's ,Epidemiologists and god knows who. All spouting "authoritatively" their own pet theories. Who are they? Where have they come from? Who cares? IT's DOING ME HEAD IN !
  15. Abbyedges Couldn't agree with you more. Maybe get the BioNTech- first dose -out to as many people as possible-then follow up later.
  16. Melthebell This is for you. https://theconversation.com/coronavirus-how-media-coverage-of-epidemics-often-stokes-fear-and-panic-131844 Timely,honest communication from a source an audience deems credible is essential to containing fear during a Pandemic. It's the alarming tone used in media coverage that unnerves me. Stay well and enjoy you Christmas and New Year.
  17. Janie48. Thanks, I love that song-and I sing it at the top of my lungs. Have a safe Christmas and New Year. 2021 has got to be better than 2020.
  18. Another media campaign of frightening the B Jesus out of everybody. Variations happen all the time, this is nothing new. New strains are tracked and vaccines can be updated - especially mRNA vaccines. As it goes, there is no need for mass panic about this particular variation. There is no evidence that any Cov-19 therapeutics has given rise to the mutation.Fears have been expressed about the effectiveness of the current vaccines. Peddling the notion that they won't work is scaremongering.In addition, what's not helpful, is having one of the country's most senior politicians,telling everybody we're put of control. Get some giddy up in the vaccination programme.
  19. El Cid You may find this interesting. https://www.sciencedirect.com/science/article/pii/S0092867420308175#bib3 Especially Para 3 in the Main Text. I'm holding onto this: Taken from the link you provided.
  20. Enntee Thank you for that direction. How on earth did UCL miss that one ?
  21. Home Open Access News Health & Social Care News Open Access News Health & Social Care News COVID-19 mutation does not make virus more infectious November 25, 2020 © Sdecoret "Researchers at University College London (UCL) have found that COVID-19 mutations do not make the virus more likely to spread, as previously feared There are currently 12,706 COVID-19 mutations. But none of them seem to make the virus more infectious. First and corresponding author Dr Lucy van Dorp (UCL Genetics Institute) said: “The number of SARS-CoV-2 genomes being generated for scientific research is staggering. We realised early on in the pandemic that we needed new approaches to analyse enormous amounts of data in close to real time to flag new mutations in the virus that could affect its transmission or symptom severity. “Fortunately, we found that none of these mutations are making COVID-19 spread more rapidly, but we need to remain vigilant and continue monitoring new mutations, particularly as vaccines get rolled out.” UCL researchers led the analysis of virus genomes from over 46,000 people across 99 countries, who tested positive for COVID-19. The mutations documented did not seem to increase transmissibility in humans, meaning that the virus would not really increase in how infectious it currently is. Three ways that COVID-19 has been mutating Coronaviruses like SARS-CoV-2 are a type of RNA virus, which can all develop mutations in three different ways: by mistake from copying errors during viral replication, through interactions with other viruses infecting the same cell (recombination or reassortment), or they can be induced by host RNA modification systems which are part of host immunity (e.g. a person’s own immune system). Most mutations are neutral, while others can be advantageous or detrimental to the virus. Both neutral and advantageous mutations can become more common as they get passed down to descendant viruses. How did the researchers know if transmission would be increased? To test if the mutations increase transmission of the virus, the researchers modelled the virus’s evolutionary tree, and analysed whether a particular mutation was becoming increasingly common within a given branch of the evolutionary tree – that is, testing whether, after a mutation first develops in a virus, descendants of that virus outperform closely-related SARS-CoV-2 viruses without that particular mutation. The researchers found no evidence that any of the common mutations are increasing the virus’s transmissibility. Instead, they found most common mutations are neutral for the virus. This includes one mutation in the virus spike protein called D614G, which has been widely reported as being a common mutation that may make the virus more transmissible. The new evidence finds that this mutation is in fact not associated with significantly increasing transmission." Where did the current variant spring from? The above article was written in November this year. What's going on? This article says the opposite. https://www.medicalnewstoday.com/articles/a-mutation-may-have-made-covid-19-more-contagious?c=970164808003 My personal opinion is with this kind of science ....Well, you couldn't put a rocket on Mars. Stay safe everybody. And have a good a Christmas as is safe to do.
  22. This not bad news. MB. Sincerely hope things go well for the "gran". Presleyl. Well done. I wish they would put some giddy up in rolling it out-so I can get mine.
  23. This is what they are going to do in Germany. Schools are going to close. https://www.cbsnews.com/news/germany-covid-lockdown-measures-winter-holidays/
  24. https://www.fda.gov/media/144245/download FDA Briefing Document. Safety data ,Page 38 and 41 . Having read it all.I'm still going to have the BioNTech vaccine -if ,in fact, that is the one I'm offered. The benefit outweighs the risk.
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