bostonaire
14-11-2004, 11:06
anyone know much about it?
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View Full Version : Ketoacidosis in relation to diabetes and infection? bostonaire 14-11-2004, 11:06 anyone know much about it? Titian 14-11-2004, 11:12 I had acidosis/ starvation ketoacidosis a number of times, not linked to diabetes. very unpleasant bostonaire 14-11-2004, 11:23 thanksfor that X.. does anyone know much about ketoacidosis in relation to diabetes and infection? JoeP 14-11-2004, 11:30 Drawing on my first degree (Biochemistry) this is where the body starts to use the Beta-oxidation pathways to break down food stuffs rather than the the mroe usual TCA cycle. The Beta-oxidation route create a load of ketones - acetoacetate, beta-hydroxybutyrate, acetone - which the body isn't really geared up to handling. Starvation Ketoacidosis starts up when the Glycogen stores of the body are depleted (as in 12-24 hours total fasting) but usually takes up to 2 weeks to become a problem. Causes thirst, tiredness, vomitting and can lead to blood pressure problems and long term health problems if it goes on. Typically in the West it's caused by eating disorders, fasting, excess excercise and insufficient food, or Atkin style dieting. There are two other types of Ketosis - Diabetic, caused by Diabetes, and Alcoholic, caused by excess alcohol intake over a long period of time with no proper food intake. Get thee to a physician if you feel you may be suffering from it. Joe bostonaire 14-11-2004, 11:56 but would like to know what is usually done apart from higher insulin doses........ .. but thanks for your input. ..does anyone know if ketones in urine and not blood is easilly put right without being hospitalised evildrneil 14-11-2004, 12:20 I would have thought the most likely (simple) cause of that would be dehydration - possibly combined with an excess of protein in the diet. However as Joe said a trip to a doc is probably indicated! bostonaire 14-11-2004, 12:27 apparantly this person isnt dehydrated and eats and drinks (non alcohol) a good diet we are baffled??? hazel 14-11-2004, 12:34 If you know anyone who is diabetic they should have a testing machine, test a spot o blood on it and you can rule out diabetes. (Use a new needle) I think between 4-7 is OK hazel JoeP 14-11-2004, 16:36 Originally posted by nitelife40 thanksfor that X.. does anyone know much about ketoacidosis in relation to diabetes and infection? I believe that an infection in people with diabetes can trigger a bout of Diabetic Ketoacidosis. Accoridng to the text books, treatment involves : Knocking out the infection. Rehydration with saline / glucose drips. Possible Insulin drips. Possible Potassium drips. But, I'm not a doctor, so get some advice! Joe Titian 14-11-2004, 17:28 are they vomiting? It depends what the infection is as sometimes they try and treat it like an allergy with antihistomines ( correct spelling?) To echo what everyone else has said though,......Go and see a doctor and don't leave it too late with something like that. The longer you leave ketoacidosis the harder it is to get under control. kittykat 14-11-2004, 19:20 It 100% depends on the level it is picked up at. If left without treatment its fatal but i suppose that can be said about a lot of conditions that the body doesnt fight off naturally. From what i know if its at a problematic, symptomatic level it will probably require hospitalisation to stabilise all the levels to normal although if the cause is known and its only mild i would think it could just be treated with drugs taken out of hospital (insulin? antibiotics?) Ill paste you the chapter on it out of a medical text book if someone lets me know theres not some kind of copywrite law against it. bostonaire 14-11-2004, 21:27 for all your posts.ive passed on the info and we thank you lots guys xx Foxxx 15-11-2004, 11:54 Originally posted by JoePritchard Drawing on my first degree (Biochemistry) this is where the body starts to use the Beta-oxidation pathways to break down food stuffs rather than the the mroe usual TCA cycle. The Beta-oxidation route create a load of ketones - acetoacetate, beta-hydroxybutyrate, acetone - which the body isn't really geared up to handling. Starvation Ketoacidosis starts up when the Glycogen stores of the body are depleted (as in 12-24 hours total fasting) but usually takes up to 2 weeks to become a problem. Causes thirst, tiredness, vomitting and can lead to blood pressure problems and long term health problems if it goes on. Typically in the West it's caused by eating disorders, fasting, excess excercise and insufficient food, or Atkin style dieting. There are two other types of Ketosis - Diabetic, caused by Diabetes, and Alcoholic, caused by excess alcohol intake over a long period of time with no proper food intake. Get thee to a physician if you feel you may be suffering from it. Joe I do wish, people would stop getting Ketosis and Ketoacidosis mixed up and referring to the Atkins diet all the time. Link below explains the difference. http://www.ketosis-ketoacidosis-difference.com/ nitelife40 - I hope your friend is ok JoeP 15-11-2004, 14:26 Originally posted by Foxxx I do wish, people would stop getting Ketosis and Ketoacidosis mixed up and referring to the Atkins diet all the time. Link below explains the difference. http://www.ketosis-ketoacidosis-difference.com/ nitelife40 - I hope your friend is ok Hiya Foxxx, There is a difference, I agree, and that's why we were referring to the Diabetic ketoacidosis. However, poor nutrition and Atkin style diets can go through normal ketosis (which everyone experiences to some degree) through to the worse condition that is ketoacidosis. The link refers to part of a site that's run by a company that creates high-protein supplements for weight control, so although I'm not saying they're biased, they may have a different perspective. Joe Titian 28-12-2004, 09:14 Originally posted by bonny are they vomiting? It depends what the infection is as sometimes they try and treat it like an allergy with antihistomines ( correct spelling?) To echo what everyone else has said though,......Go and see a doctor and don't leave it too late with something like that. The longer you leave ketoacidosis the harder it is to get under control. and to prove my point, sadly, I have just had another spell in hospital due to this and came out on the 23rd. Started feeling better Christmas day!!! |